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 REVIEW
CytoJournal 2005,  2:12

Fine-needle aspiration of the thyroid: an overview


1 Department of Laboratory Medicine and Pathology, University of Alberta Hospital, Edmonton, Alberta, Canada
2 Department of Medicine (Endocrinology and Metabolism), University of Alberta Hospital, Edmonton, Alberta, Canada

Correspondence Address:
Mark W Lee
Department of Laboratory Medicine and Pathology, University of Alberta Hospital, Edmonton, Alberta
Canada
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Source of Support: None, Conflict of Interest: None


PMID: 15987502

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Thyroid nodules (TN) are a common clinical problem. Fine needle aspiration (FNA) of the thyroid now is practiced worldwide and proves to be the most economical and reliable diagnostic procedure to identify TNs that need surgical excision and TNs that can be managed conservatively. The key for the success of thyroid FNA consists of an adequate or representative cell sample and the expertise in thyroid cytology. The FNA cytologic manifestations of TNs may be classified into seven working cytodiagnostic groups consisting of a few heterogenous lesions each to facilitate the differential diagnosis. Recent application of diagnostic molecular techniques to aspirated thyroid cells proved to be useful in separating benign from malignant TNs in several cases of indeterminate lesions.






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