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 CASE REPORT
CytoJournal 2005,  2:18

Primary small cell neuroendocrine carcinoma of the urinary bladder with coexisting high-grade urothelial carcinoma: a case report and a review of the literature


1 Department of Interdisciplinary Oncology, Division of Anatomical Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
2 Department of Pathology, University of Florida Health Science Center (UFHSC), Jacksonville, Florida, USA

Correspondence Address:
Marilyn Bui
Department of Interdisciplinary Oncology, Division of Anatomical Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
USA
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Source of Support: None, Conflict of Interest: None


PMID: 16269089

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Primary neuroendocrine carcinomas of the urinary bladder are rare. Here, we report a case of an 82-year-old man who presented with hematuria and was found to have an ulcerated lesion in the bladder. A diagnosis of small neuroendocrine cell carcinoma with coexisting minor high-grade urothelial components was rendered. In this report, the clinical, cytological, histological, and immunohistochemical features of this case are described, and a review of the literature about this neoplasm is presented. The differential diagnoses of small cell tumor in urinary bladder washing specimens are discussed.






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