Home | About CytoJournalEditorial Board | Archived articles | Search CytoJ Articles | Subscribe | Peer review policies | CytoJournal Quiz Cases
  Reviewer corner | Author corner | OA Steward’s corner | CF member’s corner | Join as CF member | Manuscript submission | Open Access (OA) Advocacy
Home
CytoJournal All 'FULL TEXT' in HTML are FREE under "open access" charter of CytoJournal.
To login for downloading any PDF OR to request TOC (Table of Content) by e-mail, please click here
Home Email this page Print this page Small font size Default font size Increase font size Cytopathology Foundation
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed8424    
    Printed91    
    Emailed0    
    PDF Downloaded352    
    Comments [Add]    
    Cited by others 6    

Recommend this journal

 

 CASE REPORT
CytoJournal 2008,  5:2

Cytological and molecular diagnosis of solid variant of papillary thyroid carcinoma: A case report


1 Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli studi di Napoli Federico II, via Pansini n°5, 80131 Naples; CEINGE, Biotecnologie Avanzate, via Comunale Margherita 482, 80145 Naples, Italy
2 Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli studi di Napoli Federico II, via Pansini n°5, 80131 Naples, Italy
3 Dipartimento di Medicina Pubblica Clinica e Preventiva, Seconda Università degli Studi di Napoli, piazza Miraglia, 80100 Naples, Italy
4 NOGEC (Naples Oncogenomic Center)-CEINGE, Biotecnologie Avanzate-Napoli, & SEMM – European School of Molecular Medicine – Naples Site, via Comunale Margherita, 482, 80145, Naples, Italy

Correspondence Address:
Giancarlo Troncone
Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli studi di Napoli Federico II, via Pansini n°5, 80131 Naples; CEINGE, Biotecnologie Avanzate, via Comunale Margherita 482, 80145 Naples
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.1186/1742-6413-5-2

Rights and Permissions

Papillary thyroid carcinoma (PTC) composed by predominant solid areas is diagnosed as a distinct variant on histological samples. Here we present a case of PTC recognized preoperatively by fine needle cytology as a solid variant. This diagnosis was made by combining cytology with the detection of the BRAFVK600-1E mutation, the molecular hallmark of the solid variant of PTC. Histological and molecular evaluation of the surgical specimen confirmed this pre-operative diagnosis. Thus combining cytology to BRAF molecular analysis is useful to refine the cytological diagnosis of this variant also on FNC specimens.






[FULL TEXT] [PDF]*


        
Print this article     Email this article

  Site Map | Copyright and Disclaimer
© 2007 - CytoJournal | A journal by Cytopathology Foundation Inc with Wolters Kluwer - Medknow
New version online since 1st July '08
Open Access