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 CASE REPORT
CytoJournal 2017,  14:19

Cytologic features of tubular adenoma of ampulla causing distal common bile duct stricture: A case report and review of the literature


1 Department of Anatomical Pathology, General Hospital, Singapore
2 Department of Gastroenterology, Cleveland Clinic, Cleveland, OH, USA
3 Department of Pathology, Cleveland Clinic, Cleveland, OH, USA

Correspondence Address:
Deborah J Chute
Department of Pathology, Cleveland Clinic, Cleveland, OH
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/cytojournal.cytojournal_2_17

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Adenomas of the ampulla of Vater are distinctly rare, representing <10% of periampullary neoplasms. Very few reports of the cytologic features of ampullary adenomas are present in literature, particularly in bile duct brushing samples. A case report and review of the literature is presented. The typical cytologic features of ampullary adenomas on cytologic preparations include tall, thin columnar cells with mildly hyperchromatic elongated nuclei and nuclear pseudostratification, in a relatively clean background. The key differential diagnostic entities include invasive adenocarcinoma, thermal artifact, and reactive atypia.






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