| CASE REPORT |
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| CytoJournal 2018, 15:23 |
Not all neck mass fine-needle aspirations with squamous cells are squamous cell carcinoma; report of a case of recurrent thyroid carcinoma with papillary and squamous components
Katie Dennis, Maura O'Neil, Anthony Harrington
Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
Correspondence Address:
Katie Dennis
Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, 3901 Rainbow Blvd, Kansas City, KS 66160
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/cytojournal.cytojournal_19_17
We report a case of a 65-year-old female who had a total thyroidectomy 12 years ago for papillary thyroid carcinoma (PTC) who presented with a recurrent thyroid bed mass. Fine-needle aspiration biopsy yielded malignant cells, consistent with squamous cell carcinoma (SCCa). Surgical resection was performed, and histologic evaluation of the mass showed mixed PTC and SCCa. The tumor cells were positive for BRAF V600E mutation. Thyroid carcinomas with admixed papillary carcinoma and SCCa are rare and are associated with aggressive behavior, high rates of metastasis, and poor outcomes. Although SCCa presenting as a neck mass is relatively common, clinical history and appropriate workup are essential for accurate diagnosis and determination of origin.
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